As I've been spending more time online than ever, I'm beginning to feel like websites are blurring together. Websites like Medium and Reddit seem to be oriented around one "kind" of content and don't really employ a bespoke content-aware approach to how it's presented. Browsers are more powerful than ever, and yet content is being drawn in more and more generic boxes. Towards that end, I went through my neverending Instapaper backlog (another way to make content appear extremely samey is to read it through an app like Instapaper, I suppose) looking for websites that are design first.
From left to right, Nippon Colors is a wonderful visualization of a color collection.
Reuters Investigates: China’s vast fleet is tipping the balance in the Pacific
Simone's Computer may take more computer juice to run than Crysis.
Gwern Branwen's Personal Website is a great example of how you can show in-context information against prose, using the humble hyperlink to provide a rich reading experience.
For more genre-defying websites, you can check out this wonderful collection at Brutalist Websites.